Flunixin meglumine, commonly referred to by the brand name Banamine®, is a non-steroidal anti-inflammatory drug (NSAID). Other common NSAIDS in animals include phenylbutazone (Bute), meloxicam, and firocoxib (Equioxx®). Below are the 5 things your veterinarians want you to know about flunixin!
Features of Banamine For Sheep
- Flunixin helps to reduce inflammation, thereby pain, and fever. Flunixin works to reduce inflammatory proteins, and by “blocking” those proteins the fever is reduced and pain is relieved. Flunixin is often recommended to reduce a fever when treating an infection, to reduce inflammation in the eyes and abdomen, and provide abdominal pain (colic pain) relief.
- Flunixin is a 12-hour drug. This means that giving more will not work better. Flunixin’s duration of action is 12 hours and should not be given more frequently than that unless directly supervised by a veterinarian. There are dangerous and life-threatening toxicities if flunixin is given at a more frequent or higher than recommended dose.
- Flunixin, like most NSAIDS, can cause GI and Kidney problems which is why we don’t want to give too much, too frequently. Flunixin can weaken the protective properties of the gastrointestinal tract, predisposing to stomach & colon ulcers. Flunixin can be dangerous to kidney function too, especially when given to a dehydrated horse or when given in combination with other medications.
- Flunixin does not cause sedation, cure colic or increase gut motility. As a pain reliever and anti-inflammatory drug some animals may become more relaxed after the medicine has taken affect, and that relaxation may cause them to appear more sedate. Flunixin can mask the symptoms of mild colic. Even if flunixin is given, the underlying cause of the colic symptoms should be investigated.
- Flunixin should not be given in the muscle, but it can be given by mouth (paste or liquid). Flunixin injectable liquid, when given in the muscle, can cause a life-threatening bacterial infection called clostridial myositis. Flunixin injectable liquid may be given by mouth to horses, just like the paste formulation. Goats, sheep, alpacas & llamas may receive flunixin injection under the skin only, not in the muscle.
Uses/benefits of Banamine For Sheep
Flunixin meglumine is a potent non-steroidal anti-inflammatory drug (NSAID) that is commonly used in veterinary medicine for its anti-inflammatory, analgesic and antipyretic properties. Like other NSAIDs, flunixin reduces inflammation by inhibiting cyclooxygenase and, in turn, decreasing the production of prostaglandins, which are important inflammatory mediators. Flunixin is known to be effective at relieving pain in various domesticated species such as horses and cattle and is currently registered for use for these animals in the USA, Europe and Australia.
Alleviation of inflammation and pain in horses, and pyrexia in cattle
- Bovine and equine drug
- Flunixin meglumine
- Relives pain and inflammation
- Controls BRD in cattle
- Supplied as a 100 ml or 250 ml bottle
Each ml of Banamine® Injectable contains flunixin meglumine equivalent to 50 mg flunixin, 0.1 mg edetate disodium, 2.5 mg sodium formaldehyde sulfoxylate, 4.0 mg diethanolamine, 207.2 mg propylene glycol; 5.0 mg phenol as preservative, hydrochloric acid, water for injection qs
Dose and administration:
Horse: The recommended dose for musculoskeletal disorders is 0.5 mg per pound (1 mL/100 lbs) of body weight once daily. Treatment may be given by intravenous or intramuscular injection and repeated for up to 5 days. Studies show onset of activity is within 2 hours. Peak response occurs between 12 and 16 hours and duration of activity is 24-36 hours. The recommended dose for the alleviation of pain associated with equine colic is 0.5 mg per pound of body weight. Intravenous administration is recommended for prompt relief. Clinical studies show pain is alleviated in less than 15 minutes in many cases. Treatment may be repeated when signs of colic recur. During clinical studies approximately 10% of the horses required one or two additional treatments. The cause of colic should be determined and treated with concomitant therapy.
Cattle: The recommended dose for cattle for control of pyrexia associated with bovine respiratory disease and endotoxemia and control of inflammation in endotoxemia is 1.1 to 2.2 mg/kg (0.5 to 1 mg/lb; 1 to 2 mL per 100 lbs) of body weight given by slow intravenous administration either once a day as a single dose or divided into two doses administered at 12-hour intervals for up to 3 days. The total daily dose should not exceed 2.2 mg/kg (1.0 mg/lb) of body weight. Avoid rapid intravenous administration of the drug. The recommended dose for acute bovine mastitis is 2.2 mg/kg (1 mg/lb: 2 mL per 100 lbs) of body weight given once by intravenous administration.
There are no known contraindications to this drug when used as directed. Intra-arterial injection should be avoided. Horses inadvertently injected intra-arterially can show adverse reactions. Signs can be ataxia, incoordination, hyperventilation, hysteria, and muscle weakness. Signs are transient and disappear without antidotal medication within a few minutes. Do not use in horses showing hypersensitivity to flunixin meglumine.
There are no known contraindications to this drug in cattle when used as directed. Do not use in animals showing hypersensitivity to flunixin meglumine. Use judiciously when renal impairment or gastric ulceration are suspected.
Prices of Banamine For Sheep
$25.99 – $54.99