Swine Influenza Vaccine

H1N1 influenza, referred to as swine flu, is a highly contagious respiratory disease in pigs caused by one of several swine influenza A viruses. Transmission of swine influenza viruses to humans is uncommon. However, the swine influenza virus can be transmitted to humans via contact with infected pigs or environments contaminated with swine influenza viruses.

Description

Swine fluTrusted Source is the result of an infection with the influenza A (H1N1) virusTrusted Source. It causes a range of symptoms that can include fever, cough, muscle and body aches. Most people recover from the flu within weeks, but some may develop a severe illness. The first swine flu outbreak in 1976Trusted Source triggered a mass vaccination program in the United States. However, the virus did not spread from its original site. The swine flu pandemic in 2009Trusted Source saw the virus spread in many countries worldwide. Scientists developed a new vaccine later that yearTrusted Source to help prevent the infection. Swine flu vaccines are safe and can prevent disease. However, the 1976 vaccine rollout caused health problems for many people who were not at risk of contracting the virus. In contrast, the successful 2009 vaccine rollout helped to end the H1N1 influenza pandemic in 2010.

the vaccine to protect against the 2009 H1N1 influenza virus will be the same for the entire 2009-2010 influenza season, which extends into the spring of 2010. The “2009” in the name only relates to the year the virus was first identified; it does not have to do with how long the vaccine will work or the year in which it should be administered. The 2009 H1N1 virus is not included in the 2009-2010 seasonal flu vaccine because it was identified after manufacturers had started making the seasonal flu vaccine.

Features of Swine Influenza Vaccine

Influenza A viruses are an important cause of acute respiratory disease in pigs and contribute to Porcine Respiratory Disease Complex along with Porcine Reproductive and Respiratory Syndrome (PRRS), Porcine Circovirus Type 2 (PCV2), Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae. Influenza A viruses of swine (IAV-S) target epithelial cells of the entire respiratory tract, replicating primarily in the lungs. As virus replication is restricted to the respiratory tract, virus transmission occurs only via the respiratory route. In pigs, influenza A infection lasts for 6–7 days and clinical signs such as fever, respiratory distress and weakness are resolved within a few days. Infection is usually mild and rarely causes death . However, this disease can cause a significant economic impact due to reproductive failure in sows due to the fever and weight loss in growing pigs. Three different influenza A virus subtypes (H1N1, H3N2, and H1N2) are currently circulating in swine worldwide. However, the origins and the antigenic characteristics of these subtypes differ from region to region throughout the world.

summarizes the IAV-S epidemiology in Europe. Briefly, the first significant influenza A virus outbreaks occurred in 1979 when an avian H1N1 virus jumped from wild ducks to pigs in Germany and Belgium. This virus is referred as European “avian-like” H1N1 (H1avN1), 1C clade based on the 2016 HA nomenclature for H1 subtype. H1avN1 viruses rapidly spread and became the predominant subtype throughout Europe . During the mid-1980s, H3N2 strains spread and became the second endemic virus subtype in Europe. Those were reassortant H3N2 viruses containing the HA and NA from a descendant of the human 1968 “Hong Kong pandemic” H3N2 and the remaining genes from H1avN1. In the mid-1990s, those H3N2 viruses reassorted with a human-seasonal H1N1 virus HA generating the H1huN2 virus lineage . These viruses also became established throughout Europe and are classified as clade 1B . For many years, those three lineages co-circulated in the different European countries keeping the epidemiological situation rather stable (. However, this situation dramatically changed with the emergence of the 2009 pandemic H1N1 virus (H1N1pdm09) . This virus was the result of reassortment between a North American “triple-reassortant” swine influenza virus and a European H1avN1 . After its introduction in Europe, this H1N1pdm09 became established and widely reassorted with pre-existing H1N1, H3N2, and H1N2 subtypes, further complicating swine influenza epidemiology (). Moreover, the H1N1pdm09 internal gene cassette extensively reassorted with domestic viruses in the UK and became the dominant backbone there.

Prices of Swine Influenza Vaccine

$40.00 – $250.00

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