IVOMEC (ivermectin) is an injectable parasiticide for swine. A low volume dose effectively kills gastrointestinal roundworms, lungworms, lice, and mange mites that may impair the health of swine. Discovered and developed by scientists from Merck Research Laboratories, ivermectin is a novel chemical entity. Its convenience, broad-spectrum efficacy and safety margin make IVOMEC Injection a unique product for parasite control in swine.
Ivermectin is derived from the avermectins, a family of potent, broad-spectrum antiparasitic agents isolated from fermentation of Streptomyces avermitilis. IVOMEC Injection is a clear, ready-to-use, sterile solution containing 1% ivermectin, 40% glycerol formal, and propylene glycol, q.s. ad 100%. IVOMEC Injection is formulated to deliver the recommended dose level of 300 mcg/kg given subcutaneously in the neck at the rate of 1 mL per 75 lb (33 kg).
Bomectin Injection for Cattle and Pigs is a ready-to-use broad-spectrum antiparasitic injection for cattle and pigs containing Ivermectin. Ivermectin is a member of the macrocyclic lactone (ML) family, which binds and interferes with invertebrate nerve and muscle cells causing parasite paralysis and death. Ivermectin has a broad-spectrum activity against both adult and larval stages of parasite nematodes.
Bomectin Injection offers reliable parasite control for both internal and external parasites. With the convenient one-shot injection, there is no splash-off so 100% of the treatment enters the animal for optimum results.
Bomectin Injection will treat and control internal parasites including gastrointestinal roundworms, lungworms, eyeworms, sucking and biting lice, mites and cattle tick in cattle, and gastrointestinal roundworms, kidney worms, lungworms, lice and mites in pigs.
Bomectin Injection for Cattle has sustained activity for:
Ostertagia spp. (Small brown stomach worm) and Cooperia spp. (Small Intestinal worm) acquired up to 7 days after treatment; and
Dictyocaulus viviparus (Lungworm) and Chrysomya bezziana (Screw Worm fly) acquired up to 14 days after treatment.
Bomectin Injection for Cattle and Pigs when used at the recommended dose level of 1mL per 50kg bodyweight (cattle) or 1mL per 33kg bodyweight (pigs) provides control of the following parasites:
Mode Of Action
Ivermectin kills certain parasitic roundworms and ectoparasites, such as mites and lice. Its action is unique and not shared by other antiparasitic agents. This action involves a chemical that serves as a signal from one nerve cell to another, or from a nerve cell to a muscle cell. This chemical, a neurotransmitter, is called gamma-aminobutyric acid or GABA. In roundworms, ivermectin stimulates the release of GABA from nerve endings and enhances binding of GABA to special receptors at nerve junctions, thus interrupting nerve impulses-thereby paralyzing and killing the parasite.
The enhancement of the GABA effect in arthropods such as mites and lice resembles that in roundworms except that nerve impulses are interrupted between the nerve ending and the muscle cell. Again, this leads to paralysis and death. The principal peripheral neurotransmitter in mammals, acetylcholine, is unaffected by ivermectin. Ivermectin does not readily penetrate the central nervous system of mammals where GABA functions as a neurotransmitter.
Dosage of Pig Wormer Ivermectin
Swine: IVOMEC Injection should be given only by subcutaneous injection in the neck of swine at the recommended dose level of 300 mcg of ivermectin per kilogram (2.2 lb) of body weight. Each mL of IVOMEC contains 10 mg of ivermectin, sufficient to treat 75 lb of body weight.