Flunixin meglumine, ketoprofen and phenylbutazone are classified with the group of compounds commonly referred to as Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). The major categories of NSAIDs include salicylates (aspirin), propionic acids (ibuprofen, fenoprofen, ketoprofen and naproxen), pyrazolones (phenylbutazone), anthranilic acids (meclofenamic acid) and aminonicotinic acids (flunixin meglumine). The NSAIDs are a diverse group compounds that are antipyreric, anti-inflammatory and analgesic agents. They share a basic mechanism of inhibiting cyclooxygenase, resulting in decreased production of prostaglandin . Flunixin meglumine was introduced into veterinary medicine in the late 1970s.
It has been used effectively in the treatment of musculoskeletal disease and colic in horse . Flunixin meglumine also is reported to reduce the adverse effects of endotoxin Toxic effects of flunixin meglumine in foals include gastrointestinal tract ulceration and diarrhea . Ketoprofen is relatively new in veterinary medicine. It was approved for use in 1990 and is recommended for alleviation of inflammation and pain associated with musculoskeletal disorders. Phenylbutazone was introduced to veterinary medicine in the 1950s and soon became the non-steroidal anti-inflammatory drug of choice in equine medicine (Phenylbutazone is indicated for treatment of various musculoskeletal disorders.
Adaptive responses to pain make chronic pain more difficult to treat than acute pain. The longer the duration and/or the more intense the pain, the more difficult it is to treat, requiring higher and/or more frequent doses of analgesics. Preventive pain management is preferred and can be performed for most elective and emergency surgical procedures. Local and general anesthetics, some tranquilizers and sedatives can alleviate much of the immediate pain associated with surgical procedures, but the effects are short-lived and do not address the longer-term post-operative pain associated with inflammation following surgery. Proper use of non-steroidal anti-inflammatory drugs (NSAIDs) can greatly reduce longer-term post-operative pain.
Although preventive pain management in cattle is preferred, more often practitioners are faced with making decisions about managing patient pain following an injury or presentation of disease. The drug classes used systemically for treating pain are opioids, alpha-2 adrenergic agonists and NSAIDs. Since the mechanism of analgesia is different for drug classes, combinations should be considered for systemic drugs or systemic and local analgesia.
Features of Phenylbutazone For Goats
Product Description: This is an anti-inflammatory and general pain reliever.
Indications for Use: Use in situations where pain relief or fever reduction is needed (infection, muscle damage, arthritis, and joint pain).Not approved for use in sheep and goats. Refer to extra-label drug use.
Dosage and Administration: Give 4.5 mg per pound per day. This means that an animal weighing 100 lbs. should receive approximately 1/2 of a 1 gram tablet.
Duration of Treatment: Continue treatment for as long as symptoms persist, but do not exceed 3 consecutive days of treatment. (See precautions.)
Packaging: This product comes in containers of 100 and 1000 tablets. Each tablet contains 1000 mg or 1 gram of phenylbutazone.
Precautions and Side Effects: Bute can cause stomach and intestinal irritation and ulceration. Be cautious regarding duration of treatment and doses. If signs of abdominal pain occur, or if there is blood or dark, tar-like material in the feces, discontinue bute and all anti-inflammatory agents immediately.
Consider antiulcer treatment such as Magnalax if necessary.
Storage: Store in a cool, dry place between 46-59°F or refrigerate.
Milk Withholding: Not established for dairy animals. Some reports indicate an “unofficial” withdrawal of 5 days.
Meat Withholding: Not established in sheep and goats. Some reports indicate an “unofficial” withdrawal of 14 days.
Drug Type: Rx
Manufacturer: Butler, Phoenix, RXV, Others
Similar Products: Aspirin
Prices of Phenylbutazone For Goats
$34.95 -$ 73.83