Oxytetracycline is a broad-spectrum antibiotic, with bacteriostatic action against a large number of Gram-positive and Gram-negative organisms (like Streptococci, Staphylococci, Pasteurella spp., Brucella spp., Corynebacteria spp., Erysipelothrix, Coliforms, Salmonella), Rickettsiae, Mycoplasmas, Chlamydia and some protozoa. Activity against Pseudomonas, Proteus- and Klebsiella spp. is low. Applied parenterally, oxytetracycline quickly penetrates the blood and tissues. The advanced effect of this preparation is the extremely long therapeutic effect. Oxytetracycline acts synergistic with polymyxin.
Oxytet 20% LA Inj. is effective against infections caused by micro-organisms susceptible to oxytetracycline, like infections of the respiratory tract (pneumonia, bronchopneumonia), infections of the urinary tract, foot rot and Bedsoniasis in sheep.
Dysentery, shipping fever, gastro-enteritis, Mycoplasmosis, (endo)metritis, mastitis, Salmonellosis and liver abscesses in cattle, pigs, sheep and goats.
Features of Oxytetracycline For Sheep
All of the tetracycline derivatives are crystalline, yellowish, amphoteric substances that, in aqueous solution, form salts with both acids and bases. They characteristically fluoresce when exposed to ultraviolet light. The most common salt form is the hydrochloride, except for doxycycline, which is available as doxycycline hyclate or monohydrate. The tetracyclines are stable as dry powders but not in aqueous solution, particularly at higher pH ranges (7–8.5). Preparations for parenteral administration must be carefully formulated, often in propylene glycol or polyvinyl pyrrolidone with additional dispersing agents, to provide stable solutions.
Tetracyclines form poorly soluble chelates with bivalent and trivalent cations, particularly calcium, magnesium, aluminum, and iron. Doxycycline and minocycline exhibit the greatest liposolubility and better penetration of bacteria such as Staphylococcus aureus than does the group as a whole. This may contribute to their efficacy in treatment of gingival diseases that may be associated with bacterial glycocalyx. Tigecycline is a glycylcycline derivative of minocycline; its large side chain decreases the risk of resistance.
Oxytetracycline Injection 200 Indications
Oxytetracycline Injection 200 is intended for use in the treatment of the following diseases in beef cattle; dairy cattle; calves, including preruminating (veal) calves; and swine when due to oxytetracycline-susceptible organisms: Oxytetracycline Injection 200 is indicated in the treatment of pneumonia and shipping fever complex associated with Pasteurella spp. and Haemophilus spp.; infectious bovine keratoconjunctivitis (pink eye) caused by Moraxella bovis; foot rot and diphtheria caused by Fusobacterium necrophorum; bacterial enteritis (scours) caused by Escherichia coli; wooden tongue caused by Actinobacillus lignieresii; leptospirosis caused by Leptospira pomona; and wound infections and acute metritis caused by strains of staphylococci and streptococci organisms sensitive to oxytetracycline.
Oxytetracycline Injection 200 can also be administered by intravenous, subcutaneous, or intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. In the treatment of severe foot rot and advanced cases of other indicated diseases, a dosage level of 5 mg/lb of body weight per day is recommended. Treatment should be continued 24-48 hours following remission of disease signs; however, not to exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of treatment. : A single dosage of 9 mg of Oxytetracycline Injection 200 per lb of body weight administered intramuscularly in the neck region is recommended in the treatment of bacterial pneumonia caused by Pasteurella multocida in swine, where re-treatment is impractical due to husbandry conditions or where repeated restraint is inadvisable.
Oxytetracycline Injection 200 can also be administered by intramuscular injection at a level of 3-5 mg of oxytetracycline per lb of body weight per day. Treatment should be continued 24-48 hours following remission of disease signs; however, not to exceed a total of 4 consecutive days. Consult your veterinarian if improvement is not noted within 24-48 hours of the beginning of treatment. For sows, administer once intramuscularly in the neck region 3 mg of oxytetracycline per lb of body weight approximately 8 hours before farrowing or immediately after completion of farrowing.
Prices of Oxytetracycline For Sheep
$147.00 – $255.00