Oral prophylactic medication with either procaine penicillin G or a mixture of chlortetracycline, sulphadimidine and procaine penicillin G reduced the incidence of streptococcal meningitis in a herd of pigs with a high recorded prevalence of the disease, but to a significant extent (P less than 0.01) only in those pigs receiving procaine penicillin G. Subsequent studies showed that after oral administration of procaine penicillin G, benzylpenicillin was detectable in plasma only at very low concentration and similar results were obtained using the potassium salt of penicillin G. However, phenoxymethyl penicillin administered orally provided high plasma concentrations of this drug. A further investigation demonstrated that despite the low plasma concentrations of penicillin after oral administration of the procaine salt, gastrointestinal and urinary concentrations of the drug were relatively high for up to five hours.
There are three types:
- Penicillin G. benzathine – This is not used orally because it is destroyed in the stomach. It is used only by injection and is very active against gram-positive bacteria including staphylococci, streptococci, erysipelothrix and clostridia and some activity against actinobacillus spp, pasteurella haemophilus and leptospira. It has a prolonged action. Penicillin G. procaine – This is slowly released giving a prolonged action.
- Acid Resistant – Phenoxymethyl penicillin – This is the oral form, it is absorbed from the digestive system and not destroyed by gastric juices.
- Semi-synthetic – Ampicillin, amoxycillin, cloxacillin – Ampicillin and amoxycillin have a wide range of activity against gram-positive and gram-negative bacteria. Cloxacillin has good activity against gram positive.
Uses/benefits of Oral Penicillin For Pigs
Pig farmers use antibiotics for treatment, metaphylaxis, prophylaxis, and growth promotion in their farm animals The relatively larger farm animal populations consume more than half the antibiotics produced globally Diseases among pigs tend to reduce productivity by reducing feed conversion efficiency, slowing growth rate, and increasing mortalities. To safeguard their investments, farmers use sublethal doses of antibiotics to prevent diseases and promote growth To reduce the volume of antibiotics used in veterinary medicine and curtail the selection of resistant bacteria, scientists and the WHO have suggested improved hygiene-based husbandry methods, veterinary supervision, and antibiotic dispensing under prescriptions only to policy makers and governments.
• One product for cattle, sheep, swine and horses• Broad spectrum activity
• Economical and effective• 48-hour milk withdrawal• Slaughter withdrawal: Cattle – 14 days, Sheep – 9 days, Swine – 7 days
• Offers uniform suspensionSyringeable through a 16-18 gauge needle
Cattle, sheep, swine and horses – 1 ml IM per 100 lbs body weight once daily. Continue treatment until recovery is apparent and for at least 1 day after symptoms disappear, usually in 2-3 days. Treatment should not exceed 4 consecutive days. Not more than 10 ml should be injected at any 1 site. Rotate injection sites for each treatment.
Prices of Oral Penicillin For Pigs
$35.52 0 $99.67