Lepto Vaccine Cattle

Leptospirosis is one of the most important and costly contributors to reproductive losses in the beef and dairy industries. Regional presence of leptospirosis in dairy herds ranged from 36% of herds in the Midwest to 91% in California, with an overall average of 59%.1 A 6 state study conducted with a cross section of environmental and management conditions representative of the U.S. beef cattle industry found overall prevalence of Lepto hardjo-bovis in cattle herds to be 42 percen

Leptospirosis is a zoonotic disease, caused by bacteria of genus Leptospira. Depending on location different serogroups are often more prevalent. Some examples of different serovars include hardjo, pomona, canicola, icterohaemorrhagiae, and grippotyphosa. Cattle are the maintentance hosts for hardjo, but as this is specialised to survive within cattle, the infection is less severe. Animals infected with other strains (such as pomona) suffer more severe illness. Maintenance hosts carry the bacteria and expose other susceptible animals. Maintenance hosts can be cattle, pigs, dogs, rodents or horses.


Leptospirosis is a worldwide bacterial disease that occurs in many species of mammals, including humans. The spiral-shaped bacteria (spirochetes) are shed in the urine and other discharges/secretions from infected or carrier animals, and can survive in moist soil or surface water for long periods at mild temperatures. If a sick, or carrier animal, urinates on pasture or hay, or in a pond or stream, susceptible animals may pick up spirochetes when eating/drinking contaminated feed or water, or when walking through contaminated water or having it splash into the eyes, nose or mouth.

Daniel Grooms, Michigan State University, says there is always risk for exposure for beef cattle since the disease is carried by wildlife and rodents. “Studies have shown that about 50 percent of beef herds in the U.S. are infected, with at least one animal in the herd carrying Leptospirosis hardjo, the serovar that is host-adapted to cattle. We see more incidence of lepto (all types) in warm, moist climates An animal may be infected by serovars maintained by its own species (maintenance host infection or host-adapted infection) or serovars maintained by other species (incidental infection or nonhost-adapted infection). Leptospirosis is transmitted either directly between animals or indirectly through the environment.


The clinical signs of Lepto depend on the herd’s degree of resistance or immunity, the infecting serovar, and the age of the animal infected.

Features of Lepto Vaccine Cattle

Leptospirosis is caused by thin, spiral-shaped Leptospira bacteria. Most infections in cattle are caused by the following types of Leptospira:

Leptospira borgpetersenii serovar Hardjo type hardjo-bovis

L. interrogans serovar Hardjo type hardjo-prajitno

L. interrogans serovar Pomona

L. kirschneri serovar Grippotyphosa
Two other serovars are known to infect cattle and are generally included in leptospirosis vaccines, but the maintenance hosts are species other than cattle:

L. interrogans serovar Icterohaemorrhagiae (maintenance host is the rat) 

L. interrogans serovar Canicola (maintenance host is the dog)

The most common cause of bovine leptospirosis in the U.S. is Leptospira borgpetersenii serovar Hardjo type hardjo-bovis.

Features of Lepto Vaccine Cattle

Lepto 3-Way® is an inactivated leptospirosis vaccine containing the serovars HardjoCopenhageni and Pomona – the serovars most commonly identified with disease in livestock and humans in New Zealand. Lepto 3-Way® stimulates the immune system of calves and adult cattle to produce antibodies against these serovars, stopping their shedding in urine, and reducing the risk of leptospirosis infections in humans.

  • No added adjuvant, meaning reduced injection site reactions, ease of syringeability and minimal settling in packs & injectors
  • Able to be used for 30 days after the pack is opened
  • Can be used in at-risk calves from 4 weeks of age

Prices of Lepto Vaccine Cattle

$40.00  – $139.99

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