Gumboro Disease Vaccine

The poultry industry has evolved significantly in recent decades. The increasing demand for higher volumes, better quality and competitive prices have resulted in the industrialization, intensification and concentration of production. The latter has led to increasing pressure on animals that have better genetic, productive and efficiency potential. In this context, the control of infectious diseases is key. Additionally, the pressure to reduce the use of antibiotics has increased, as the demands on the effective control of zoonotic agents, which has forced producers to improve and deeply understand disease control.

Biosecurity and vaccination are essential tools for the proper control of infectious diseases. Additionally, the concepts of vaccination have undergone such a revolution that they have required the definition of new health strategies. Infectious Bursal Disease (IBD) or, more commonly known as Gumboro disease, has historically caused great losses to industrial poultry and is classified as one of the main diseases in almost all countries of the world.


Inactivated (or killed) Gumboro vaccines contain a high amount of inactivated whole or subunit IBD virus presented in a mineral oil emulsion. These vaccines are used to boost MDA in breeders. This way the breeders will transfer a higher level of maternal delivered antibodies to the progeny.

Conventional live attenuated Gumboro vaccines are live attenuated Gumboro viruses that replicate in the bursa of Fabricius, resulting in immunity generated by the replication of the whole virus. There are different Gumboro disease virus strains used in the vaccines and there are different levels of attenuation: Vaccine types are categorised into four groups:

  • ‘Mild’ which are highly attenuated
  • ‘Intermediate’ which are very attenuated
  • ‘Intermediate Plus’ which are moderately attenuated
  • ‘Hot’ which are poorly attenuated

For this type of vaccine, the MDA levels should be monitored. If given too early, in the presence of an excessively high level of MDA, the virus in the vaccine is neutralised or its replication is delayed. If it is given too late, a window of opportunity (also called the protection gap) is offered to the farm virus to infect the flock. This optimal timing depends on the level of MDA and the invasiveness of the vaccine, that is, its capacity to overcome a given titer of MDA.

Dosage and Administration:

One drop of GumboMed Plus Vet vaccine should be administered by eye/nasal instillation or administered through drinking water at 10-14 days old Broilers/Layers/Breeder or other poultry as a primary dose. A booster dose should be given after 7 days of primary dose.


Nobilis® Gumboro D78 is a live freeze-dried vaccine containing live Infectious Bursal Disease (Gumboro) virus strain D78 with stabilisers. Each dose contains at least 4,0 log10 TCID50 of Infectious Bursal Disease (Gumboro) virus strain D78. The freeze-dried vaccine pellet contains stabilisers and gentamycin.


  • Store in the dark between 2 °C and 8 °C.
  • Do not freeze.
  • Avoid prolonged or repetitive exposure to high ambient temperatures, following       withdrawal from the refrigerator prior to use.
  • Protect from exposure to direct sunlight.


  • Vaccinate healthy chickens only.
  • It is advisable to vaccinate all the susceptible chickens on the farm at the same time.
  • If this is not feasible, strict separation of vaccinated and unvaccinated chickens should be done to prevent the spread of the vaccine virus to the unvaccinated chickens.
  • Do not mix Nobilis® Gumboro D78 with other vaccines.
  • Use according to the number of doses as indicated on the label.
  • Do not open and reconstitute the vaccine until ready to start vaccination.
  • Use Nobilis® Gumboro D78 immediately after reconstitution.
  • Do not store partially used vaccine vials for future use.
  • Destroy any empty containers as well as unused, reconstituted vaccine and vaccination equipment according to local waste disposal regulations after completion of vaccination.
  • Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

Prices of Gumboro Disease Vaccine

$12.95 – $65.00

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