Doxy-Gen 20/20 wsp is a combination preparation containing gentamycin and doxycycline and provides a broad antibacterial spectrum covering the most microbial agents producing diseases in animals. Gentamycin belongs to the group of amino-glycoside antibiotics and has bactericidal action. It has a broad antibacterial spectrum and is active against Gram-positive and Gram-negative bacteria (including: Pseudomonas spp., Klebsiella spp., Enterobacter spp., Serratia spp., E. coli, Proteus spp., Salmonella spp., staphylococci). Moreover, it is active against Campylobacter fetus subsp. jejuni and Treponema hyodysenteriae. Gentamycin may be active against bacteria which are resistant to other amino-glycoside antibiotics (like Neomycin, Streptomycin, Kanamycin).
Doxycycline is a tetracycline antibiotic with bacteriostatic action against a large number of Gram-positive and Gram-negative bacteria (like Staphylococcus spp., Haemophilus influenza, E. coli, Corynebacteria, Bacillus anthracis, some Clostridium spp., Actinomyces spp., Brucella spp., Enterobacter spp., Salmonella spp., Shigella spp. and Yersinia spp.). It also acts against Mycoplasma spp., Rickettsiae and Chlamydia spp. Gentamycin is not absorbed from the gastrointestinal tract and therefore acts locally. Following oral administration, doxycycline is rapidly absorbed from the gastrointestinal tract and produces a therapeutic blood level quickly, which persists for a long period, as doxycycline has a relatively long-serum half-life. Doxycycline has a great affinity to lung tissues, therefore it is recommended especially for respiratory tract infections. This combination provides an intensive antibacterial effect in the gastrointestinal tract and a rapid and intensive systemic effect after absorption. Doxy-Gen 20/20 wsp is a potent antibacterial product and useful in most infective diseases in the targeted animals.
Doxycycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria, like Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Doxycycline is also active against Chlamydia, Mycoplasma and Rickettsia spp. The action of doxycycline is based on inhibition of bacterial protein synthesis. Doxycycline has a great affinity to the lungs and is therefore especially useful for treatment of bacterial respiratory infections.
Features of Doxycycline For Pigs
For the treatment of the clinical signs associated with porcine respiratory disease caused by Actinobacillus pleuropneumoniae, Pasteurella multocida, and Mycoplasma hyopneumoniae susceptible to doxycycline.Chickens: Where clinical disease is present in the flock, to reduce mortality, morbidity, and clinical signs and to reduce lesions due to Pasteurellosis caused by Pasteurella multocida or to reduce morbidity and lesions in respiratory infections caused by Ornithobacterium rhinotracheale (ORT).
Dosage and administration
TO BE ADMINISTERED ORALLY VIA DRINKING WATERChickens:The recommended dose is 10 mg doxycycline hyclate (20 mg product) per kg body weight per day for 3-4 consecutive days in case of infections caused by P. multocida and 20 mg doxycycline hyclate (40 mg product) per kg body weight per day for 3-4 consecutive days in case of infections caused by O. rhinotracheale.Pigs:The recommended dose is 12.5 mg doxycycline hyclate (25 mg product) per kg body weight per day for 4 consecutive days.If no improvement in clinical signs is seen within this time, the diagnosis should be reviewed and treatment changed. In case of severe infections the medication period may be prolonged for a maximum of 8 consecutive days as determined by the attending veterinary surgeon.Based on the dose to be used, and the number and weight of the animals to be treated, the exact daily amount of product can be calculated
Gastrointestinal and respiratory infections caused by doxycycline sensitive micro-organisms, like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus and Streptococcus spp. in calves, goats, poultry, sheep and swine.
Hypersensitivity to tetracyclines.
Administration to animals of a seriously impaired hepatic function.
Concurrent administration with penicillins, cephalosporins, quinolones and cycloserine.
Administration to animals with an active microbial digestion.
Discoloration of teeth in young animals may occur. Hypersensitivity reactions may occur.
Dosage of Doxycycline For Pigs
For oral administration via feed or drinking water.
- Poultry : 100 g per 300 litres of drinking water during 3 – 5 days.
- Calves : 100 g per 60 calves of 50 kg bodyweight during 4 – 6 days.
- Pigs : 100 g per 200 litres of drinking water during 4 – 6 days.
Mixed with feed the product should be used immediately. Medicated drinking water should be used within 24 hours.
– For meat:
Calves, goats and sheep : 14 days.
Swine : 8 days.
Poultry : 7 days.
Not for use in animals from which milk or eggs are produced for human consumption.
Prices of Doxycycline For Pigs
$15.90 – $58.50