Clostridium Vaccine Sheep

Santa Cruz Animal Health offers a premium line of ovine Clostridial vaccines for the prevention of diseases in sheep caused by Clostridial organisms such as Blackleg, Enterotoxemia, Malignant Edema, Black Disease, Gas-gangrene and Red Water. These vaccines are safe for use in all sheep including lambs, ewes and rams. Choose from top selling products by Merck, Boehringer Ingelheim, Zoetis, Novartis and Colorado Serum. Protect your sheep from a variety of Clostridial diseases with ovine Clostridial vaccines from Santa Cruz Animal Health.


Vaccination is frequently practiced for protection of animals against clostridial diseases. A wide variety of vaccines is available, singly or in combinations that consist of bacterins, toxoids, or mixtures of bacterins and toxoids. Single vaccination with most clostridial vaccines does not provide adequate levels of protection and must be followed by a booster dose within 3–6 weeks. Vaccination of young animals does not yield adequate protective immunity until they are at least 1–2 months old. Therefore, most vaccination strategies target the pregnant dam so that maximal immunity is transferred to the neonate via colostrum. Most commercial vaccines are inactivated and usually contain 2-, 4-, 7-, or 8-way combinations of clostridial organisms/toxoids. These should be optimally timed for provision of maximal protection at the most likely age of susceptibility.

Tetanus toxoid is commonly administered as a single vaccine in horses but is often administered in combination in sheep, goats, and cattle. In sheep and goats, a common combination is tetanus toxoid plus Clostridium perfringens types C and D. In cattle, a combination frequently administered in feedlots is a 4-way vaccine that consists of killed cultures of C chauvoeiC septicumC novyi, and C sordellii to protect against blackleg and malignant edema. A more complex clostridial vaccine that contains C perfringens types C and D in addition to the components of the 4-way vaccine may be administered to protect cattle against enterotoxemias as well. The addition of C haemolyticum extends the protection to include bacillary hemoglobinuria. The clostridial vaccines often cause tissue reactions and swelling and should therefore be administered to cattle in the neck and by the subcutaneous rather than the intramuscular route.

Features of Clostridium Vaccine Sheep

Preventable infectious diseases can have a severe economic and welfare impact on a sheep flock. When the obvious visible symptoms appear, the infectious disease is established, losses are to be expected and treatment effectiveness is variable. Prevention is more cost effective and economically efficient when the sub-clinical and chronic losses are accounted for.

Clostridial diseases are caused by a group of bacteria that have the ability to form resistant spores. Spores can concentrate in areas of high sheep usage e.g. around yards, sheds and troughs. They are resistant to extremes in temperature and can survive in soil for many years. Disease occurs only when the spore is present in damaged body tissue which provides the right conditions for the bacteria to germinate and to produce toxins. The signs of disease are caused by the toxins produced by these bacteria, not the bacteria themselves.

Prices of Clostridium Vaccine Sheep


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