Cl Vaccine For Goats

Corynebacterium pseudotuberculosis, the bacterium that causes the disease CL, is spread from animal to animal primarily through contact with material from subcutaneous abscesses (pus) or fomites (inanimate objects) contaminated with abscess material. The organism can survive several months in the soil and environment, remaining a source of infection. Though much less common than visible subcutaneous abscesses, internal abscesses may also form in the lungs and abdominal organs as a result of spread of the organism within the animal via blood or lymph. When abscesses are present in the lungs, the organism may be transmitted through respiratory secretions (nasal discharge or coughing). In rare cases, C. pseudotuberculosis may be present in the milk. Although CL is not sexually transmitted, it is recommended to avoid natural breeding of animals with abscesses in order to prevent transmission via close contact.


Caseous lymphadenitis (CL) is a chronic, contagious disease caused by the bacterium Corynebacterium pseudotuberculosis. Although prevalence of CL varies by region and country, it is found worldwide and is of major concern for small ruminant producers in North America. The disease is characterized by abscess formation in or near major peripheral lymph nodes (external form) or within internal organs and lymph nodes (internal form). Although both the external and internal forms of CL occur in sheep and goats, the external form is more common in goats, and the internal form is more common in sheep.

Economic losses from CL include death, condemnation and trim of infected carcasses, hide and wool loss, loss of sales for breeding animals, and premature culling of affected animals from the herd or flock. Once established on a farm or region (endemic), it is primarily maintained by contamination of the environment with active draining lesions, animals with the internal form of the disease that contaminate the environment through nasal discharge or coughing, the ability of the bacteria to survive harsh environmental conditions, and lack of strict biosecurity necessary to reduce the number and prevent introduction of new cases. Although CL is typically considered a disease of sheep and goats, it also occurs more sporadically in horses, cattle, camelids, swine, wild ruminants, fowl, and people. Because of its zoonotic potential, care should be taken when handling infected animals or purulent exudate from active, draining lesions.

Features of Cl Vaccine For Goats

Unfortunately, infected animals remain infected for life, and CL does not respondto most antibiotics. Studies on the appropriate antibiotic, dose, or withdrawal times of various antibiotics used experimentally to attempt to control CL in goats are not available, so are not recommended as treatment. Use of antibiotics to treat infections that do not respond to antibiotic treatment,  such as CL, can increase the growing problem of antimicrobial resistance as well as waste time and money.

Abscesses can be drained or surgically removed. Draining leads to contamination of the environment, requiring the goat to be isolated until the abscess heals completely – approximately 20-30 days later. The environment then needs to be thoroughly cleaned and disinfected. Surgical removal is not practical for most producers – it removes the abscess without draining it so the bacteria is not released into the environment, but requires the goat to be anesthetized for the delicate surgical procedure. Consult with your herd veterinarian about whether draining or removing abscesses is the right choice for your herd. There is a CL vaccine available in the United States for goats. In Canada, there is a vaccine for sheep, but it is not recommended for use in goats due to the high frequency of adverse reactions such as fever, swelling at the infection site, and abortion.

Benefits of Cl Vaccine For Goats

Despite the fact that CL is not a leading cause of morality, potential production losses and concern for animal welfare should encourage producers to reduce the occurrence of the disease. Producers should aim to prevent CL from entering their herd by practicing strict biosecurity and screening all new stock or stock returning from off-property. Producers can control and eradicate CL from their herd with careful management and maintaining separate infected and uninfected herds. The goal of vaccination is to stimulate an immune response that provides some level of protection from disease. Unfortunately, most vaccines do not achieve complete protection from infection and subsequent disease. Vaccines are expected to reduce the severity of disease in infected animals or limit the frequency of disease in the herd.

Many factors, including nutrition, stresses, and the general health of animals, can influence the effectiveness of vaccination. Vaccines should be administered according to label directions and only to systemically healthy animals. Consult your veterinarian for guidance when designing and implementing a herd vaccination program. Vaccines should not be expected to eliminate all disease problems and should be considered only as a tool to be used with other management strategies to mitigate the occurrence and impacts of infectious diseases.


  • Vaccines not 100% effective
    • Boosters, accurate records needed
    • Vaccine will NOT cure, only help prevent abscesses
    • Using vaccine creates “seropositives”
  • Testing and culling seropositives: best method

Prices of Cl Vaccine For Goats


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