Autogenous Vaccine Swine

Vaccination involves exposing the pig to the protein components (called the antigen) of the infectious agent. Some vaccines contain living organisms that have been altered so that they cannot produce disease but still produce an immunity. Most contain killed or inactivated organisms. The immune system responds by producing antibodies that destroy the infectious agents, usually in co-operation with specialised body cells or by neutralising the toxins that are responsible for the disease. This process of stimulating immunity is called vaccination. Vaccines contain antigens from viruses, bacteria, bacterial toxins, or parasites. They are given to pigs, usually by injection, to stimulate an immune response which will protect the pigs against later natural infection with the organism from which the vaccine was derived. Most stimulate both a humoral response and a cell-mediated response.

Vaccines can either contain viable organisms that will multiply in the pig, or inactivated ones that will not multiply in the pig. In live vaccines the organism has usually been attenuated (i.e. its virulence has been reduced) so that although it multiples in the pig it does not normally cause disease. Examples are the PRRS vaccine, aujeszky’s disease (pseudorabies) vaccines and classical swine fever vaccines. Live attenuated vaccines have the advantage that because they multiply in the pig they give a bigger antigenic stimulus resulting in stronger longer-lasting immunity. They have the disadvantage that they may become inactivated in wrong storage conditions (e.g. heat) or during dosing, by exposure to antiseptics or disinfectants, and are then useless. It is also important that they are stable and not able to return to full virulence.


An autogenous vaccine is a killed vaccine made by a veterinarian custom for a specific producer or group of animals.  Autogenous vaccines were previously made only in veterinary clinics; however, many individuals question the sterility of these processes due to limited testing procedures. After all, these are veterinary clinics and not vaccine laboratories. With many different samples, people, etc., entering and exiting a veterinary clinic on a regular basis, there was always a risk of contamination in the vaccine with an unintended pathogen. Because of the risks and issues, veterinarians were traditionally hesitant to recommend an autogenous vaccine. However, they are used more and more frequently today. 

Features of Autogenous Vaccine Swine

Autogenous vaccines are an important herd health tool. But, at times, they have been touted as a panacea without any basis in fact.Autogenous vaccines are an important herd health tool. They fill a void when new disease agents emerge for which there are no vaccines, or when antigenic variation occurs that is outside the spectrum of protection afforded by commercially available vaccines.


1. A disease is identified, or other interventions have been ineffective.
2. A veterinarian collects samples and submits to a diagnostic laboratory.
3. The diagnostic lab determines the cause and isolates the pathogen.
4. The isolates are forwarded to an autogenous vaccine company.
5. The autogenous company grows the bacteria or virus in the lab.
6. A vaccine is developed, and quality control testing is performed.
7. The vaccine is shipped to the customer.

It’s important to note that an autogenous vaccine cannot be used as an immediate intervention for a disease problem, as the entire process can take anywhere from 6 to 12 weeks.

Prices of Autogenous Vaccine Swine


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