Amprolium For Poultry

One of the most common ailments chickens can suffer is coccidiosis. Coccidia are parasites on chickens, which infect the chicken’s stomach tissue upon ingestion. Once attached to the tissue, the organism starts to multiply and spread. In severe cases, this will cause bleeding within the intestinal tract or cecal, which starts to have a negative impact on the animal’s health. If left untreated, coccidia can be fatal. Smart backyard chicken keepers keep Amprolium on hand and use as it as a preventative measure against this fatal illness.

Amprolium HCl is an anti-protozoal drug and in chemical structure analogue to thiamine (vitamin B1). It inhibits the use of thiamine by the protozoal parasites. Amprolium is a coccidiostat (antiprotozoal) used for the treatment and prevention of coccidiosis in calves, sheep, goats, chickens (broilers and breeders) and other fowl such as turkeys, with activity against Eimeria spp., especially Eimeria tenella and Eimeria necatrix. It is a thiamine (vitamin B1) analogue and its pharmacological effect relies on competitive inhibition of thiamine uptake. Amprolium competitively inhibits the active transport of thiamine in isolated second-generation schizonts of Eimeria spp. and in host intestinal cells. Upon ingestion of amprolium, the coccidia experience thiamine deficiency and starve from malnutrition.

Indications

Amprolin-300 WS is indicated for coccidiosis caused by coccidia susceptible to amprolium (Eimeria spp.) or gastrointestinal infections for which it is therapeutically or prophylactically indicated to administer amprolium in calves, goats, sheep and poultry. Amprolium 250 wsp is a concentrated powder of Amprolium HCl, water-soluble for use in drinking water of poultry, calves, lambs, young goats, cattle and sheep. It is used as a preventive or therapeutic agent against Eimeria infections in poultry, especially E. tenella, E. necatrix, E. acervulina and E. praecox.

It is effective against other protozoal infections like Histomoniasis (Blackhead) in turkeys and poultry; against coccidiosis in calves, sheep and goats; against amaebiasis in various species.

Side effects of Amprolium For Poultry

Overdosage of amprolium can suppress weight gain in broilers and cause polyneuritis. Long-term administration of amprolium in high doses may result in thiamine (vitamin B1) deficiency in the host. To treat amprolium overdose, thiamine should be administered parenterally or orally. Long-term treatment of high doses may result in delayed growth or poly-neuritis (caused by reversible thiamine deficiency). The development of natural immunity may be delayed.

Uses/benefits of Amprolium For Poultry

It is quarternized derivative of pyrimidine which is a thiamine antagonist. It is most active against E. tenella, E. necatrix and E. acervulina and to lesser extent E. maxima. It could be fed at several times the recommended dose with no ill effects and probably, one of the safest anti-coccidial drugs to be used extensively. There is no premarketing withdrawal requirement for this compound.

Dosage/administration:

For oral administration via feed or drinking water.

  • Poultry : 100 – 150 g per 100 litres of drinking water during 5 – 7 days, followed by 25 g per 100 litres of drinking water during 1 or 2 weeks. During treatment medicated drinking water should be the only source of drinking water.
  • Calves, lambs, kids : 3 g per 20 kg bodyweight as drench during 1 – 2 days, followed by 7.5 kg per 1,000 kg of feed during 3 weeks.
  • Cattle, sheep : 3 g per 20 kg bodyweight during 5 days (via drinking water).

Mixed with feed, the product should be used immediately. Medicated drinking water should be used within 24 hours.
If no improvement is noted within 3 days, evaluate the symptoms to determine the presence of other diseases. Follow the instructions of your veterinarian or poultry pathologist.

Withdrawal period:

Meat : 3 days
Milk : 3 days

Prices of Amprolium For Poultry

 $29.95 – $35.99

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