Amoxicillin is semisynthetic broad-spectrum penicillin with a bactericidal effect against gram-positive and gram-negative bacteria. It is used in the treatments of gastrointestinal, respiratory and urinary tract infections caused by amoxicillin sensitive micro-organisms, like Campylobacter, Clostridium, Corynebacterium, E. coli, Erysipelothrix, Haemophilus, Pasteurella, Salmonella, penicillinase negative Staphylococcus and Streptococcus spp. in calves, cattle, goats, sheep, and swine.
The antibiotic is bound to a special binding protein, the synthesis of the cell wall is inhibited by the blockage of synthesis of peptidoglycan, and autolytic enzymes are activated in the cell wall resulting in wall lesions and cell death.
Amoxycillin long-acting is a broad-spectrum, semi-synthetic penicillin, active against both Gram-positive and Gram-negative bacteria. The range of effect includes Streptococci, not penicillinase-producing Staphylococci, Bacillus anthracis, Corynebacterium spp., Clostridium spp., Brucella spp., Haemophilus spp., Pasteurella spp., Salmonella spp., Moraxella spp., E. coli, Erysipelothrix rhusiopathiae, Fusiformis, Bordetella spp., Diplococci, Micrococci and Sphaerophorus necrophorus. Amoxycillin has many advantages; it is non-toxic, has good intestinal resorption, is stable in acidic conditions and is bactericidal. The drug is destroyed by e.g. penicillinase-producing staphylococci and some Gram-negative strains.
Features of Amoxicillin For Cattle
Amoxicillin is an half synthetic penicillin. The long acting formulation allows the antibiotic to reach and maintain effective levels of Amoxicillin for 48 hours.
The main advantages of Amoxicillin are :
• broad spectrum antibiotic,
• bactericidal action enhanced,
• excellent diffusion and high concentration into all tissues after single administration through intramuscular route,
• low percentage of linkage with serum proteins,
• quick therapeutical answers,
• no pain nor irritation at the injection site.
Administration and Dosage
Usual dosage is as follows: 10 mg of amoxicillin per kg body weight (intramuscularly and subcutaneously) in pig, sheep, dog, cattle and swine or 1 ml per 15 kg of live weight per day.
Shake well before use and do not administer more than 20 ml in cattle, more than 10 ml in swine and more than 5 ml in calves, sheep and goats per injection site.
Not for use in sheep and goats producing milk for human consumption.
Protection period: meat of cattle 15 days; meat of pigs 42 days; cow’s milk: 72 hours.
Guidelines on dosage and administration should be referred by veterinary doctor. Completion of treatment without exceeding the advised dosage is always recommended.
Meat : 14 days
Milk : 3 days
Prices of Amoxicillin For Cattle
$20.90 – $199.55