8 Way Vaccine For Cattle

Vaccination programs for beef cattle herds are designed to protect the animals from diseases caused by infectious organisms such as viruses, bacteria, and protozoans. Vaccines stimulate an animal’s immune system to produce a protective response against an organism. The immune system will then “remember” how to produce a response against the organism if it ever is infected with that organism. Vaccines cannot prevent exposure to infectious organisms, but they do increase an animal’s ability to fight off an infection or lessen the severity of the disease if it occurs. The majority of cattle vaccines are injected, although some may be given by other routes, such as intranasal and oral. Although antibiotics are also often administered via injection, treating an animal with one of these drugs is not a vaccination but rather a treatment once an infection has occurred.

Animal health product manufacturers go to great expense to obtain approval for vaccines from the U.S. Department of Agriculture. They must prove that the vaccine is
safe and that it will do what the label claims it will do. See Extension publication ANR-1416, “Understanding Protection Claims on Vaccine Labels,” for more information. Vaccine trade names can be confusing; however, the label will always specify which diseases and microorganisms the vaccine provides protection against. Sometimes different terms used in the name can be confusing as well. Terms such as 4-way, 5-way, 7-way, or 8-way do not refer to any particular type of vaccine, but rather to the number of different subtypes of a microorganism in a vaccine. These terms are most often used for leptospirosis or clostridial disease vaccines, which contain several subtypes of the Leptospira or Clostridium organisms.


One Shot Ultra® 8 is effective for vaccination of healthy cattle against disease caused by Clostridium chauvoei, Cl. septicum, Cl. haemolyticum, Cl. novyi, Cl. sordellii, Cl. perfringens Types B, C and D, and respiratory disease caused by Mannheimia haemolytica Type A1.

Help protect your cattle and sheep against major clostridial diseases with one convenient combination vaccine. Covexin® 8 is for the vaccination of healthy cattle and sheep as an aid in the prevention of the following clostridial diseases of cattle and sheep:

  • Blackleg (Clostridium chauvoei)
  • Malignant edema (Cl. septicum)
  • Red water (Cl. haemolyticum)
  • Black disease (Cl. novyi)
  • Tetanus (Cl. tetani)
  • Enterotoxemia and Enteritis (Cl. perfringens types B, C and D)

Although Clostridium perfringens type B is not a significant problem in cattle and sheep living in North America, immunity is provided by the beta toxoid of type C and the epsilon toxoid of type D. This clostridial combination vaccine contains killed cultures and does not require reconstitution prior to administration. Covexin® 8 should be administered subcutaneously to cattle and sheep, with a second dose repeated 6 weeks later. Annual revaccination with a single dose is recommended. May be administered to pregnant cows and calves nursing pregnant cows. Do not administer within 21 days before slaughter.

Dosage And Administration

Shake well. Using aseptic technique, inject subcutaneously or intramuscularly.

Dosage: 5 mL, repeated in three (3) to four (4) weeks. Revaccinate annually or prior to periods of extreme risk, or parturition. For Cl. novyi and Cl. haemolyticum, revaccinate every five (5) to six (6) months. Animals vaccinated under three (3) months of age should be revaccinated at weaning or at four (4) to six (6) months of age.

Intramuscular injection: Make intramuscular injections deeply into a large muscle (thigh). Cleanse the area and insert the needle. The needle should be at least 3/4″ in length.

Subcutaneous injection: Can be made in any area where the skin fits loosely (neck, chest wall, armpit or flank). Lift the skin to facilitate needle entry, insert the needle and discharge the dose. Massage the area to accelerate distribution.


Use the entire contents when first opened. Anaphylactic reactions may occur following use of this product. This product has been tested under laboratory conditions and shown to meet all federal standards for safety and ability to immunize normal, healthy animals. The level of performance of this product may be affected by conditions of use such as stress, weather, nutrition, disease, parasitism, other treatments, individual idiosyncrasies or impaired immunological competency. These factors should be considered by the user when evaluating the product performance or freedom from reactions.

Prices of 8 Way Vaccine For Cattle

$12.79 – $34.39

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