5 In 1 Vaccine For Puppies

Vaccination is important for preventing serious diseases from affecting your dog. But why give your pet five shots when they could get what they need in one? For dogs, several of the most common vaccines are typically given together in a single shot that’s known as the DHPP vaccine, 5-in-1 vaccine for dogs, or 5-way puppy shot.

This combination vaccine is considered a core vaccine, which means all dogs should receive it regardless of their lifestyle. Core vaccines tend to protect against viruses that are highly contagious, cause serious disease, and have high fatality rates. Here’s what pet parents should know about the DHPP vaccine, aka the 5-in-1 vaccine for dogs, including the diseases it protects against and how often it’s administered. 


For vaccination of healthy dogs 6 weeks of age or older against canine distemper virus (CDV), canine adenovirus type 1 (CAV1), canine adenovirus type 2 (CAV2), canine parainfluenza virus (CPiV), canine parvovirus (CPV), and canine parvovirus type 2c (CPV2c).

Features of 5 In 1 Vaccine For Puppies

DHPP is a canine vaccine that prevents distemper, parvovirus, parainfluenza, and two types of adenovirus (hepatitis). Dogs should receive the DHPP vaccine at 8, 12, and 16 weeks, one year later, and then 1 to 3 years after that. Previously, dogs received DHPP yearly afterward. However new research by several vaccine manufacturers has led to the approval of vaccines good for 3 years in adult dogs that have received all puppy vaccines and a vaccination one year after their puppy set. This is due to a build up of long term memory cells. Memory cells slowly die off after vaccination so only dogs with full vaccination histories will have enough cells to last 3 years. Dogs with missed vaccinations will need to be vaccinated more often.


Effective for vaccination of healthy dogs 6 weeks of age or older against canine distemper virus (CDV), canine adenovirus type 1 (CAV1), canine adenovirus type 2 (CAV2), canine parainfluenza virus (CPiV), canine parvovirus (CPV), and canine parvovirus type 2c (CPV2c).

Benefits of 5 In 1 Vaccine For Puppies

The 5-in-1 vaccine for dogs offers many advantages over single-pathogen vaccines. For one thing, your dog will only need to receive one shot during each visit rather than five, which saves time and money and minimizes your pet’s discomfort. This combo vaccine can even include noncore vaccines, like leptospirosis, which means your pup can get maximum protection without having to get multiple shots. Extensive research studies have shown that the 5-in-1 vaccine is generally safe for dogs, including puppies as young as 6 weeks old. Any side effects encountered are typically rare and mild, such as temporary soreness at the injection site.

Vanguard DAPP contains attenuated strains of CDV, CAV2, CPiV and CPV. The high-titer, low-passage CPV virus in Vanguard DAPP is highly immunogenic and capable of stimulating active immunity in the presence of maternal antibodies. This product does not contain CPV type 2c. Cross protection against CPV type 2c was demonstrated in vaccinated puppies challenged 5 weeks following second vaccination. CAV2 cross-immunizes against CAV1 to help protect dogs against infectious canine hepatitis without producing post-vaccination side effects, including uveitis and corneal opacity, sometimes associated with CAV1 vaccines.

Vaccination Schedule

Before you even pick up your puppy – whether it’s from a breeder, a shelter, or a friend – you should have a visit to the vet scheduled. Ideally, you take your pup to the vet before you even bring him/her home for the first time. The sooner the better so that your vet can give your puppy a proper examination, including a fecal check for intestinal parasites, and help you schedule your puppy’s shots. The exact schedule for puppy vaccines will depend on the above-mentioned factors and your vet’s recommendations, but generally, puppies start getting vaccines at around six weeks of age and continue through 5 months of age, followed by annual or semi-annual booster shots depending on the need.

It is important to note that at certain ages, certain dogs are not capable of “responding” to certain vaccines – that is, mounting a good antibody defense to the vaccine and thus building immunity to it. This can be very hard to judge and varies from breed to breed and litter to litter and depends on how much “passive immunity” the mother has already passed down to the puppy through the colostrum via nursing during the first 36 hours of life. Generally, though, puppies are most responsive to vaccines between the ages of 6 and 18 weeks.

Prices of 5 In 1 Vaccine For Puppies

$17.99 – $49.99

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